Associate Professor, Ophthalmology, Wayne State University School of Medicine
Ophthalmology
Dr. Bret A. Hughes, MD
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Bret Hughes is an expert in the field of Ophthalmology. He attended Tulane University School of Medicine. He received 1 awards: "Fellow (FAAO)". Bret A. Hughes, MD is a published doctor. He has 59 publications published. The most current publication "The additive effect of latanoprost to maximum-tolerated medications with low-dose, high-dose, or no pilocarpine therapy." He accepts all Medicare patients.
Publications
- KCNQ and KCNE Potassium Channel Subunit Expression in Bovine Retinal Pigment Epithelium.
- Characterization of the R162W Kir7.1 mutation associated with snowflake vitreoRetinopathy.
- Effects of KCNQ Channel Modulators on the M-type Potassium Current in Primate Retinal Pigment Epithelium.
- KCNQ5/Kv5 Potassium Channel Expression and Subcellular Localization in Primate Retinal Pigment Epithelium and Neural Retina.
- Activation of P2X receptors induces apoPtosis in human retinal pigment epithelium.
- Regulation of Kir channels in bovine Retinal pigment epithelial cells by phosphatidylinositol 4,5-bisphosphate.
- Modulation of the Kir7.1 potassium channel by extracellular and intracellular pH.
- CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion.
- Spatial and temporal expression of MFRP and its interaction with CTRP5.
- The effect of the timing of scleral flap suture release on the safety and long-term success of phacotrabeculectomy.
- A three-month, multicenter, double-masked study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to travoprost 0.004% ophthalm...
- Comparison of long-term outcomes of selective laser trabeculoplasty versus argon laser trabeculoplasty in open-angle Glaucoma.
- Toll-like receptor 4 (TLR4) of Retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments.
- Preliminary investigation into the expression of proton-coupled oligopeptide transporters in neural retina and Retinal pigment epithelium (RPE): lack of functional act...
- Expression of the inwardly rectifying K+ channel Kir2.1 in native bovine corneal endothelial cells.
- Expression and localization of the inwardly rectifying potassium channel Kir7.1 in native bovine Retinal pigment epithelium.
- Long-term filtration and visual field outcomes after primary Glaucoma triple procedure with and without mitomycin-C.
- Fluid transport across Retinal pigment epithelium is inhibited by cyclic AMP.
- Assessment of swelling-activated Cl- channels using the halide-sensitive fluorescent indicator 6-methoxy-N-(3-sulfopropyl)quinolinium.
- Adenylate cyclase stimulation alters transport in frog Retinal pigment epithelium.
- Voltage-dependent currents in isolated cells of the frog Retinal pigment epithelium.
- Exogenous endophthalmitis initially treated without systemic antibiotics.
- cAMP stimulates the Na+-K+ pump in frog Retinal pigment epithelium.
- Direct evidence for a basolateral membrane Cl- conductance in toad Retinal pigment epithelium.
- Effects of cyclic AMP on fluid absorption and ion transport across frog Retinal pigment epithelium. Measurements in the open-circuit state.
- Four-point fixation technique for sutured posterior chamber intraocular Lenses.
- Tumor cell invasion of model 3-dimensional matrices: demonstration of migratory pathways, collagen disruption, and intercellular cooperation.
- Effects of current clamp on chick Retinal pigment epithelium.
- Apical electrogenic NaHCO3 cotransport. A mechanism for HCO3 absorption across the Retinal pigment epithelium.
- Membrane polarity of the Na(+)-K+ pump in primary cultures of Xenopus Retinal pigment epithelium.
- Anterior segment trauma and air bags.
- Effects of Ba2+ and Cs+ on apical membrane K+ conductance in toad Retinal pigment epithelium.
- An outwardly rectifying K+ current active near resting potential in human Retinal pigment epithelial cells.
- Isolated bovine Retinal pigment epithelial cells express delayed rectifier type and M-type K+ currents.
- ATP-dependent regulation of inwardly rectifying K+ current in bovine Retinal pigment epithelial cells.
- cAMP-activated chloride currents in amphibian Retinal pigment epithelial cells.
- Properties of the inwardly rectifying K+ conductance in the toad Retinal pigment epithelium.
- Neuropeptide Y and the Retinal pigment epithelium: receptor subtypes, signaling, and bioelectrical responses.
- Inwardly rectifying K+ currents in isolated human Retinal pigment epithelial cells.
- The additive effect of latanoprost to maximum-tolerated medications with low-dose, high-dose, or no pilocarpine therapy.
- Use of fascia lata in revision of filtration surgery.
- Analysis of reliability indices from Humphrey visual field tests in an urban Glaucoma population.
- Topical verapamil in Glaucoma filtration surgery.
- Long-term outcome of primary Glaucoma triple procedure with adjunctive 5-fluorouracil.
- Expression and permeation properties of the K(+) channel Kir7.1 in the Retinal pigment epithelium.
- Molecular cloning and expression of an inwardly rectifying K(+) channel from bovine corneal endothelial cells.
- Cloning and functional expression of human Retinal kir2.4, a pH-sensitive inwardly rectifying K(+) channel.
- Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraOcular pressure spike after argon laser trabeculoplasty.
- Primary Glaucoma triple procedure in patients with primary open-angle Glaucoma: the effect of mitomycin C in patients with and without prognostic factors for filtratio...
- Limbus-based vs fornix-based conjunctival flap in combined glaucoma and Cataract surgery with adjunctive mitomycin C.
- Comparative study of silicone versus acrylic foldable Lens implantation in primary glaucoma triple procedure.
- Adjunctive subconjunctival mitomycin C in Glaucoma triple procedure.
- Primary Glaucoma triple procedure with or without adjunctive mitomycin. Prognostic factors for filtration failure.
- Human, but not bovine, photoreceptor outer segments prime human Retinal pigment epithelial cells for metabolic activation and massive oxidant release in response to li...
- Expression of Kir7.1 and a novel Kir7.1 splice variant in native human Retinal pigment epithelium.
- Comparison of initial intraOcular pressure response with topical beta-adrenergic antagonists and prostaglandin analogues in African American and white individuals in t...
- Regulation of inwardly rectifying K+ channels in Retinal pigment epithelial cells by intracellular pH.
- Expression of inwardly rectifying potassium channel subunits in native human Retinal pigment epithelium.
Schools
Tulane University School Of Medicine
Charity HospTulane
Harlem Hospital
University South Fla Tampa
Kresge Eye Institute
Procedures Preformed
- Cataract Removal Surgery
- Eyelid Surgery
- Glaucoma Surgery
- Vitrectomy (incl. Macular Hole Repair)
Conditions Treated
- Aphakia and Other Disorders of Lens
- Astigmatism
- Blindness
- Cataract
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Doctors Specialties
- Ophthalmology
Accepted Insurances
Awards
- Fellow (FAAO)
Education
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University of South Florida -
Tulane University -
Tulane University School of Medicine
Hospital
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DMC - Children's Hospital of Michigan -
DMC Harper University Hospital -
John D. Dingell Veterans Affairs Medical Center
Drug Facts
| NPI NUMBER | 1760420822 | |
| NPPES Provider LastName | HUGHES | |
| NPPES Provider FirstName | BRET | |
| NPPES Provider ZIPCode | 482011423 | |
| NPPES Provider State | MI | |
| Specialty Description | Ophthalmology | |
| Total Claim Count | 3893.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1760420822 |
| Last Name Of The Provider | HUGHES |
| First Name Of The Provider | BRET |
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