Professor, Surgery, Wayne State University School of Medicine

General Surgery

Doctor Lawrence N. Diebel, MD works in the field of General Surgery. He studied medicine at Wayne State University School of Medicine. Wayne State University School of Medicine has a rank of 63 in research and a 85 in primary care He received 1 awards: "Fellow (FACS)". Lawrence Diebel is also published. He has 85 publications published. The lastest publication: "Effect of hypertonic saline solution and dextran on ventricular blood flow and heart-lung interaction after hemorrhagic shock.' He accepts Medicare.

Publications

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• Phosphatidylcholine and the intestinal mucus layer: in vitro efficacy against Clostridium difficile-associated polymorphonuclear neutrophil activation.
• Estrogen modulates intestinal mucus physiochemical properties and protects against oxidant injury.
• Exogenous phosphatidylcholine supplementation improves intestinal barrier defense against Clostridium difficile toxin.
• Salutary effect of calcium channel blockade following hypoxic and septic insult.
• Multicenter review of diaphragm pacing in spinal cord injury: Successful not only in weaning from ventilators but also in bridging to independent respiration.
• Organ failure in the obese adipocytes prime polymorphonuclear cell inflammation under stress conditions.
• Patterns of early mortality after trauma in a neighborhood urban trauma center: can we improve outcomes?
• Effect of host defenses on Clostridium difficile toxin-induced intestinal barrier injury.
• Changes in lymph proteome induced by hemorrhagic shock: The appearance of damage-associated molecular patterns.
• Estrogen modulation of pneumonia? An immunoglobulin A effect.
• H2 blockers decrease gut mucus production and lead to barrier dysfunction in vitro.
• Estrogen impairs pulmonary microvascular response to gut-derived mediators after shock conditions.
• Gender dimorphism in the gut: mucosal protection by estrogen stimulation of IgA transcytosis.
• Disparate effects of bacteria and toll-like receptor-dependant bacterial ligand stimulation on immunoglobulin a transcytosis.
• The significance of a serum creatinine in defining renal function in seriously injured and septic patients.
• Sequence of immunoglobulin isotype exposure modulates inflammatory response to bacteria and lipopolysaccharide in vitro.
• Secretory immunoglobulin A abrogates inflammatory responses and improves mortality after pseudomonas pneumonia.
• Dose-dependent effects of ethanol and E. coli on gut permeability and cytokine production.
• Intestinal epithelial cells mediate lung injury after ethanol exposure and hypoxic insult.
• Systemic not just mesenteric lymph causes neutrophil priming after hemorrhagic shock.
• The relative roles of bacteria and host inflammatory cells in SIgA degradation.
• Cleavage of SIgA by gram negative respiratory pathogens enhance neutrophil inflammatory potential.
• Systemic not just mesenteric lymph causes acute lung injury following hemorrhagic shock.
• Secretory immunoglobulin a blunts gut-mediated priming of neutrophils in vitro.
• The synergistic effect of ethanol and shock insults on Caco-2 cytokine production and apoptosis.
• The intestinal epithelial cell modulates the effect of alcohol on neutrophil inflammatory potential.
• Ethanol effects proinflammatory state of neutrophils in shock.
• T-cell cytokines affect mucosal immunoglobulin A transport.
• A comparative study of secretory immunoglobulin A and immunoglobulin G in host defense in an in vitro pneumonia model.
• Immunoglobulin a modulates inflammatory responses in an in vitro model of pneumonia.
• Intestinal epithelial cells modulate PMN activation and apoptosis following bacterial and hypoxic challenges.
• The pivotal role of tumor necrosis factor-alpha in signaling apoptosis in intestinal epithelial cells under shock conditions.
• Immunoglobulin A protease is a virulence factor for gram-negative pneumonia.
• Enterocyte apoptosis and barrier function are modulated by SIgA after exposure to bacteria and hypoxia/reoxygenation.
• The synergistic effects of hypoxia/reoxygenation or tissue acidosis and bacteria on intestinal epithelial cell apoptosis.
• Rapid diagnosis of an ulnar fracture with portable hand-held ultrasound.
• The effects of varying oxygen conditions and immunoglobulin A on barrier defense to bacterial invasion.
• Ethanol impairs intestinal barrier defense by modulation of immunoglobulin A transport.
• Actin mediates secretory immunoglobulin A transport: effect of ethanol.
• Advanced ultrasonic diagnosis of extremity trauma: the FASTER examination.
• Effect of intra-abdominal pressure on abdominal wall blood flow.
• End-diastolic volume versus pulmonary artery wedge pressure in evaluating cardiac preload in trauma patients.
• Gastric intramucosal acidosis in patients with chronic kidney failure.
• Effect of sepsis and 3,5,3'-triiodothyronine replacement on myocardial integrity during oxidant challenge.
• Gallbladder and biliary tract candidiasis.
• Effects of deferoxamine on H2O2-induced oxidative stress in isolated rat heart.
• Effects of increasing airway pressure and PEEP on the assessment of cardiac preload.
• Effect of triiodothyronine augmentation on rat lung surfactant phospholipids during sepsis.
• Effect of thyroid hormone (T3)-responsive changes in surfactant apoproteins on surfactant function during sepsis.
• Effect of inhibition of lipid peroxidation on myocardial oxidant damage.
• Regional differences in lymphocyte function following resuscitated hemorrhagic shock.
• Right ventricular response after myocardial contusion and hemorrhagic shock.
• Balloon tamponade for liver injuries: case report.
• Effect of increased intra-abdominal pressure on hepatic arterial, portal venous, and hepatic microcirculatory blood flow.
• Electrolyte and acid-base changes with massive blood transfusions.
• Fibrin gel limits intra-abdominal adhesion formation.
• End-diastolic volume. A better indicator of preload in the critically ill.
• Antibiotic-primed fibrin gel improves outcome in contaminated splenic injury.
• Effect of increased intra-abdominal pressure on mesenteric arterial and intestinal mucosal blood flow.
• A comparison of passive and active shunting for bypass of the retrohepatic IVC.
• Cardiopulmonary complications after major surgery: a role for epidural analgesia?
• Hypertonic saline/dextran improves septic myocardial performance.
• Clostridial splenic abscess: diagnosis, treatment, and outcome.
• Nonoperative management of gunshot wounds of the abdomen.
• Triiodothyronine (T3) supplementation maintains surfactant biochemical integrity during sepsis.
• Splanchnic mucosal perfusion effects of hypertonic versus isotonic resuscitation of hemorrhagic shock.
• Retroperitoneal approach to first lumbar vertebral body.
• Secretory immunoglobulin A blocks hypoxia-augmented bacterial passage across Madin-Darby canine kidney cell monolayers.
• Splanchnic ischemia and bacterial translocation in the abdominal compartment syndrome.
• Signaling of apoptotic lung injury by lipid hydroperoxides.
• The effects of bacterial overgrowth and hemorrhagic shock on mucosal immunity.
• Effect of hypertonic saline solution and dextran on ventricular blood flow and heart-lung interaction after hemorrhagic shock.
• Synergistic effect of hyperoxia and immunoglobulin A on mucosal barrier defense.
• Hemorrhagic shock impairs mucosal immunity to gut-derived antigens.
• Thoracic ultrasound diagnosis of pneumothorax.
• Effect of acute hemodilution on intestinal perfusion and intramucosal pH after shock.
• Prospective evaluation of thoracic ultrasound in the detection of pneumothorax.
• Sequential changes in mucosal immunity after hemorrhagic shock.
• In-vivo particle mediated delivery of mRNA to mammalian tissues: ballistic and biologic effects.
• Synergistic effects of Candida and Escherichia coli on gut barrier function.
• An in vitro model to assess mucosal immune function and bacterial translocation.
• Clinical practice guideline: endpoints of resuscitation.
• Clinical practice guideline: red blood cell transfusion in adult trauma and critical care.
• Calcium blockade reduces renal apoptosis during ischemia reperfusion.

Schools

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• Wayne State University School Of Medicine

• Fairview University Med Center

Doctors Specialties

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• Critical Care Surgery
• General Surgery

Accepted Insurances

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• Choice Plus POS II
• Blue Card PPO
• Blue Cross Blue Shield of Illinois PPO
• Blue Care Network PCP Focus Network
• Group Employees PPO
• Cigna HMO
• Cigna PPO
• Great West Healthcare-Cigna PPO
• Open Access Plus
• Cofinity PPO
• Commercial Insurance Company
• Coventry Health Care
• Preferred PPO
• Choice Care PPO
• Medicaid
• Medicare MCR
• Molina
• MultiPlan PPO
• PHCS Network PPO
• Priority PPO
• Choice Plus POS
• Navigate HMO
• Navigate POS
• Options PPO
• United Healthcare

Awards

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• Fellow (FACS)

Education

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• Wayne State University School of Medicine
• University of Minnesota at Fairview

Hospital

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• DMC - Detroit Receiving Hospital
• DMC Harper University Hospital

Drug Facts

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NPI NUMBER		1124068093
NPPES Provider LastName		DIEBEL
NPPES Provider FirstName		LAWRENCE
NPPES Provider ZIPCode		48201
NPPES Provider State		MI
Specialty Description		General Surgery
Total Claim Count		99.0
Distinct Opioid Count		1.0
Opioid Claim Count		39.0
Percent Opioid Claims		39.39

Helpful Reviews

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Medicare Facts

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National Provider Identifier [NPI]	1124068093
Last Name Of The Provider	DIEBEL
First Name Of The Provider	LAWRENCE
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