Associate Professor, Neurology, University of California, Irvine College of Medicine
Neurology
Dr. Michael Demetriou, MD
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Michael Demetriou practices Neurology. Dr. Michael Demetriou has written publications. He has 22 publications published with PubMed. The lastest paper is: 'N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca(2+) signaling.' He accepts all Medicare patients.
Publications
- N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca(2+) signaling.
- Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms.
- Membrane biophysics define neuron and astrocyte progenitors in the neural lineage.
- Hypomorphic MGAT5 polymorphisms promote Multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants.
- Incorporating parental information into family-based association tests.
- Pathogenesis of Multiple sclerosis via environmental and genetic dysregulation of N-glycosylation.
- N-acetylglucosamine inhibits T-helper 1 (Th1)/T-helper 17 (Th17) cell responses and treats experimental autoimmune encephalomyelitis.
- N-Glycans differentially regulate eosinophil and neutrophil recruitment during allergic airway inflammation.
- Genetics and the environment converge to dysregulate N-glycosylation in Multiple sclerosis.
- Manipulating cell surface glycoproteins by targeting N-glycan-galectin interactions.
- Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with Multiple sclerosis.
- Metabolism, cell surface organization, and disease.
- Adaptive regulation at the cell surface by N-glycosylation.
- T cell receptor signaling co-regulates Multiple Golgi genes to enhance N-glycan branching.
- T-cell growth, cell surface organization, and the galectin-glycoprotein lattice.
- Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
- N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration.
- Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis.
- Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.
- N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells.
- UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice.
Schools
University Of Toronto Faculty Of Medicine
Procedures Preformed
- EEG (Electroencephalogram)
Conditions Treated
- Carpal Tunnel Syndrome
- Convulsions
- Dementia
- Dystonia
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Doctors Specialties
- Neurology
Accepted Insurances
Hospital
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UC Irvine Medical Center
Drug Facts
| NPI NUMBER | 1992885099 | |
| NPPES Provider LastName | DEMETRIOU | |
| NPPES Provider FirstName | MICHAEL | |
| NPPES Provider ZIPCode | 92868 | |
| NPPES Provider State | CA | |
| Specialty Description | Neurology | |
| Total Claim Count | 457.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1992885099 |
| Last Name Of The Provider | DEMETRIOU |
| First Name Of The Provider | MICHAEL |
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