Professor, Physiology, Tulane University School of Medicine
Cardiology
Dr. Patrice Delafontaine, MD
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Patrice Delafontaine works in the field of Cardiology. He has 6 awards "Regional Top Doctor", "CMS Meaningful Use Stage 1 Certification", "Fellow (FACP)", "Elected Member", "Fellow (FACC)" and "Super Doctor". Patrice Delafontaine is also a published MD. He has 100 paper published. The most recent paper is: Distinct and common pathways in the regulation of insulin-like growth factor-1 receptor gene expression by angiotensin II and basic fibroblast growth factor. Doctor Patrice Delafontaine, MD accepts Medicare.
Publications
- Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs.
- Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase.
- Urinary Creatinine Excretion, Bioelectrical Impedance Analysis, and Clinical Outcomes in Patients with CKD: The CRIC Study.
- Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.
- Angiotensin type 2 receptor signaling in satellite cells potentiates skeletal muscle regeneration.
- Natural disasters and Myocardial infarction: the six years after hurricane katrina.
- Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5' Stem-loop of COL1a...
- Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration.
- Acetylsalicylic Acid Inhibits IL-18-Induced Cardiac Fibroblast Migration through the Induction of RECK.
- Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: Potential therapeutic targets for cardiac cachexia.
- Angiotensin II Inhibits Satellite Cell Proliferation and Prevents Skeletal Muscle Regeneration.
- Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.
- Persistent giant U wave inversion with anoxic brain injury.
- Insulin-like growth factor-1 regulates glutathione peroxidase expression and activity in vascular endothelial cells: Implications for atheroprotective actions of insul...
- Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling.
- A Longitudinal Study of Left Ventricular Function and Structure from CKD to ESRD: The CRIC Study.
- Effect of Hurricane Katrina on Chronobiology at Onset of Acute Myocardial Infarction During the Subsequent Three Years.
- Aging, atherosclerosis, and IGF-1.
- Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function.
- In-vivo measurements of wall shear stress in human Coronary arteries.
- Effect of uniaxial, cyclic stretch on the morphology of monocytes/macrophages in culture.
- Identification of two positive transcriptional elements within the 91-base pair promoter for mouse testis angiotensin converting enzyme (testis ACE).
- Gamma-irradiation markedly inhibits the hydrated collagen gel contradiction by arterial smooth muscle cells.
- IRS-1 variant: A new risk factor for Coronary artery disease?
- Sequence of a cDNA encoding dog insulin-like growth factor I.
- Growth factors and vascular smooth muscle cell growth responses.
- Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor.
- The growth hormone and insulin-like growth factor 1 axis in Heart failure.
- Secondary signalling mechanisms in angiotensin II-stimulated vascular smooth muscle cells.
- Estrogen effects on insulin-like growth factor-I (IGF-I)-induced cell proliferation and IGF-I expression in native and allograft vessels.
- Angiotensin II causes weight loss and decreases circulating insulin-like growth factor I in rats through a pressor-independent mechanism.
- Characterization of insulin-like growth factor-I and its receptor and binding proteins in transected nerves and cultured Schwann cells.
- Angiotensin II Modulation of Insulin-like Growth Factor I Expression in the Cardiovascular System.
- Growth factors and receptors in allograft arteriosclerosis.
- Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells.
- Insulin-like growth factor I and its binding proteins in the cardiovascular system.
- Aortic and renal regulation of the renin-angiotensin system in interrenal Aortic coarctation.
- Endothelin A and B receptors are down-regulated in the Hearts of hypertensive rats.
- The angiotensin II AT1 receptor is tyrosine and serine phosphorylated and can serve as a substrate for the src family of tyrosine kinases.
- Estradiol decreases IGF-1 and IGF-1 receptor expression in rat Aortic smooth muscle cells. Mechanisms for its atheroprotective effects.
- Potassium depletion selectively inhibits sustained diacylglycerol formation from phosphatidylinositol in angiotensin II-stimulated, cultured vascular smooth muscle cells.
- Induction of cardiac insulin-like growth factor I gene expression in pressure overload hypertrophy.
- Epitope mapping of the alpha-chain of the insulin-like growth factor I receptor using antipeptide antibodies.
- Abdominal coarctation increases insulin-like growth factor I mRNA levels in rat aorta.
- Oxidized low-density lipoprotein is associated with apoptosis of vascular smooth muscle cells in human atherosclerotic plaques.
- Insulin-like growth factor I gene expression in vascular cells.
- Correlation of receptor sequestration with sustained diacylglycerol accumulation in angiotensin II-stimulated cultured vascular smooth muscle cells.
- Angiotensin II stimulates tyrosine phosphorylation and activation of insulin receptor substrate 1 and protein-tyrosine phosphatase 1D in vascular smooth muscle cells.
- Differential effects of low density lipoproteins on insulin-like growth factor-1 (IGF-1) and IGF-1 receptor expression in vascular smooth muscle cells.
- Angiotensin II regulates insulin-like growth factor I gene expression in vascular smooth muscle cells.
- Translation initiation of the insulin-like growth factor I receptor mRNA is mediated by an internal ribosome entry site.
- Fibroblast growth factor regulates insulin-like growth factor-binding protein production by vascular smooth muscle cells.
- Regulation of insulin-like growth factor I receptors on vascular smooth muscle cells by growth factors and phorbol esters.
- Regulation of insulin-like growth factor I messenger RNA levels in vascular smooth muscle cells.
- G-protein coupled and tyrosine kinase receptors: evidence that activation of the insulin-like growth factor I receptor is required for thrombin-induced mitogenesis of ...
- Tumor necrosis factor-alpha regulates insulin-like growth factor-1 and insulin-like growth factor binding protein-3 expression in vascular smooth muscle.
- Thrombin stimulates phosphorylation of insulin-like growth factor-1 receptor, insulin receptor substrate-1, and phospholipase C-gamma 1 in rat Aortic smooth muscle cells.
- Distinct and common pathways in the regulation of insulin-like growth factor-1 receptor gene expression by angiotensin II and basic fibroblast growth factor.
- G-protein and tyrosine kinase receptor cross-talk in rat Aortic smooth muscle cells: thrombin- and angiotensin II-induced tyrosine phosphorylation of insulin receptor ...
- Transcriptional regulation of the insulin-like growth factor-I receptor gene: evidence for protein kinase C-dependent and -independent pathways.
- Insulin-like growth factor 1 binding protein 3 synthesis by Aortic endothelial cells is a function of cell density.
- Regulation of vascular smooth muscle cell insulin-like growth factor I receptors by phosphorothioate oligonucleotides. Effects on cell growth and evidence that sense t...
- Hypertension increases insulin-like growth factor binding protein-4 mRNA levels in rat aorta.
- Decreased expression of insulin-like growth factor-1 and apoptosis of vascular smooth muscle cells in human atherosclerotic plaque.
- Insulin-like growth factor binding protein-4 expression is decreased by angiotensin II and thrombin in rat Aortic vascular smooth muscle cells.
- Angiotensin II stimulates gene expression of cardiac insulin-like growth factor I and its receptor through effects on blood pressure and food intake.
- Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA.
- Thrombin regulates insulin-like growth factor-1 receptor transcription in vascular smooth muscle: characterization of the signaling pathway.
- Angiotensin II activation of insulin-like growth factor 1 receptor transcription is mediated by a tyrosine kinase-dependent redox-sensitive mechanism.
- Angiotensin II induces skeletal muscle wasting through enhanced protein degradation and down-regulates autocrine insulin-like growth factor I.
- Angiotensin II Infusion Induces Marked Diaphragmatic Skeletal Muscle Atrophy.
- Angiotensin II Reduces Food Intake by Altering Orexigenic Neuropeptide Expression in the Mouse Hypothalamus.
- Effect of hurricane katrina on incidence of Acute myocardial infarction in new orleans three years after the storm.
- Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.
- β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and Myocardial...
- Angiotensin II Upregulates Protein Phosphatase 2C{alpha} and Inhibits AMP-Activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting.
- Angiotensin II, oxidative stress and skeletal muscle wasting.
- Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.
- Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy.
- Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice.
- Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation.
- The effect of nebivolol versus metoprolol succinate extended release on asymmetric dimethylarginine in Hypertension.
- Symptoms characteristic of Heart failure among CKD patients without diagnosed Heart failure.
- Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway.
- Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation.
- Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque s...
- EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 si...
- IGF-1 prevents ANG II-induced skeletal muscle atrophy via Akt- and Foxo-dependent inhibition of the ubiquitin ligase atrogin-1 expression.
- Vitamin C and percutaneous Coronary intervention.
- WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.
- IGF-1, oxidative stress and atheroprotection.
- Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.
- Effect of Hurricane Katrina on the incidence of Acute coronary syndrome at a primary angioplasty center in New Orleans.
- Intravenous hMSCs improve Myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6.
- Insulin glargine reduces Carotid intimal hyperplasia after balloon catheter injury in Zucker fatty rats possibly by reduction in oxidative stress.
- Calcific constrictive pericarditis with refractory hypokalemia in a patient with Gitelman's Syndrome.
- IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.
- The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor.
- Enhancing repair of the mammalian Heart.
Schools
Universite De Geneve Faculte De Medecine
Monmouth Med Center
Hahnemann Hospital
Brigham Womens HospHarvard
Procedures Preformed
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac Myocardial Perfusion Imaging
- Cardioversion, Elective
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Conditions Treated
- Aneurysm and Dissection of Heart
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- Aortic Valve Disease
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Regional Top Doctor
- CMS Meaningful Use Stage 1 Certification
- Fellow (FACP)
- Elected Member
- Fellow (FACC)
- Super Doctor
Education
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Brigham and Women's Hospital -
Drexel University - Hahnemann University Hospital -
Monmouth Medical Center -
University of Geneva Faculty of Medicine
Drug Facts
| NPI NUMBER | 1063526523 | |
| NPPES Provider LastName | DELAFONTAINE | |
| NPPES Provider FirstName | PATRICE | |
| NPPES Provider ZIPCode | 701122600 | |
| NPPES Provider State | LA | |
| Specialty Description | Cardiology | |
| Total Claim Count | 915.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1063526523 |
| Last Name Of The Provider | DELAFONTAINE |
| First Name Of The Provider | PATRICE |
| View All |
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