Board Certified Plastic Surgeon
Plastic Surgery
Dr. Scott W. Mosser, MD
|
|
Give Review
Dr. Scott W. Mosser is an expert in the field of Plastic Surgery. He graduated from Baylor College of Medicine. He received 2 awards: "Super Doctor" and "Fellow (FACS)". Dr. Scott W. Mosser is a published physician. He has 51 publications published. The most current publication "Potent, non-thiol inhibitors of farnesyltransferase."
Publications
- Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine.
- [(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor.
- Plantar flap reconstruction for acral lentiginous melanoma.
- Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.
- Potent benzimidazolone-based CGRP receptor antagonists.
- Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay.
- NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles.
- Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
- Orally efficacious NR2B-selective NMDA receptor antagonists.
- Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918.
- Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chirality.
- Identification of potent, highly constrained CGRP receptor antagonists.
- Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: development of novel spiropiperidines.
- Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility.
- Synthesis and evaluation of novel tricyclic benzo[4.5]cyclohepta[1.2]pyridine derivatives as NMDA/NR2B antagonists.
- The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists.
- The discovery of highly potent CGRP receptor antagonists.
- Alpha-hydroxy amides as a novel class of bradykinin B1 selective antagonists.
- Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin...
- Calcitonin gene-related peptide (CGRP) receptor antagonists: investigations of a pyridinone template.
- Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-...
- Caprolactams as potent CGRP receptor antagonists for the treatment of migraine.
- Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists.
- Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N...
- Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists.
- Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: optimization of the 4-substituted piperidine.
- Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead.
- Conformational restriction of flexible ligands guided by the transferred noe experiment: potent macrocyclic inhibitors of farnesyltransferase.
- High-performance liquid chromatography/mass spectrometry characterization of Ki4B-Ras in PSN-1 cells treated with the prenyltransferase inhibitor L-778,123.
- Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.
- N-arylpiperazinone inhibitors of farnesyltransferase: discovery and biological activity.
- Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.
- Potent, non-thiol inhibitors of farnesyltransferase.
- N-Arylalkyl pseudopeptide inhibitors of farnesyltransferase.
- A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control ...
- Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library.
- 2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase.
- Inhibition of Ras function in vitro and in vivo using inhibitors of farnesyl-protein transferase.
- Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.
- Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway.
- Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.
- Pseudopeptide inhibitors of Ras farnesyl-protein transferase.
- Protein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude mice.
- Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages.
- NMR studies of novel inhibitors bound to farnesyl-protein transferase.
- Pseudodipeptide inhibitors of protein farnesyltransferase.
- Identification of amino acid residues required for Ras p21 target activation.
- Sequence dependence of protein isoprenylation.
- Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes.
- Steady-state kinetic mechanism of Ras farnesyl:protein transferase.
Schools
Baylor College Of Medicine
University Hospital Inc
California Pacific Med CtrCalifornia
Doctors Specialties
- Plastic Surgery
Accepted Insurances
Awards
- Super Doctor
- Fellow (FACS)
Education
-
Case Western Reserve University - University Hospitals -
Case Western Reserve University - MetroHealth -
California Pacific Medical Center -
Baylor College of Medicine
Hospital
-
Saint Francis Memorial Hospital -
California Pacific Medical Center
Helpful Reviews
Similar Doctors
|
|
Dr. Ghazi A. Althubaiti, MD |
|
Dr. Larry K. Fan, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Shahin M. Javaheri, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Usha Rajagopal, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Michael L. Brownstein, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Jeffrey E. DeWeese, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Stephen P. Daane, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Andrew J. Watt, MD |
|
|
Dr. John A. Romano, MD |