Professor, Medicine, UCLA School of Medicine
Pulmonology
Dr. Steven M. Dubinett, MD
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Steven M. Dubinett works in the field of Pulmonology. He went to medical school at Rutgers New Jersey Medical School. Rutgers New Jersey Medical School is ranked 76 in research and 0 in primary care medicine He over the years received 1 awards: "Super Doctor". Steven M. Dubinett is a published doctor and has 100 publications published. The lastest was: 'MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.'
Publications
- MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.
- Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers.
- Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway.
- Loss of miR-125a expression in a model of K-ras-dependent Pulmonary premalignancy.
- PGE2-Driven Expression of c-Myc and OncomiR-17-92 Contributes to Apoptosis Resistance in NSCLC.
- A Cytokine-Delivering Polymer Is Effective in Reducing Tumor Burden in a Head and Neck Squamous Cell Carcinoma Murine Model.
- Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer.
- A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis.
- MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis.
- Challenge and opportunity of targeted lung cancer chemoprevention.
- TLR3 agonists and proinflammatory antitumor activities.
- Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer.
- Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer.
- Targeting MDSCs enhance therapeutic vaccination responses against lung cancer.
- Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1.
- Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells.
- Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.
- Myeloid suppressor cell depletion augments antitumor activity in lung cancer.
- Mitotic inhibitors.
- The Inflammatory Tumor Microenvironment, Epithelial Mesenchymal Transition and Lung Carcinogenesis.
- Mast cells and histamine enhance the proliferation of non-small cell lung cancer cells.
- Lung cancer chemoprevention with celecoxib in former smokers.
- Role of CXCR3 Ligands in IL-7/IL-7R{alpha}-Fc-Mediated Antitumor Activity in Lung Cancer.
- Elevated levels of CXC chemokine connective tissue activating peptide (CTAP)-III in lung cancer patients.
- Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma.
- Evolving concepts in lung carcinogenesis.
- Novel CCL21-Vault Nanocapsule Intratumoral Delivery Inhibits Lung Cancer Growth.
- Poly(ADP-ribose) polymerase inhibitors.
- Novel drugs--miscellaneous category.
- National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection...
- Histopathologic findings of HPV and p16 positive HNSCC.
- Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
- Chemokines: can effector cells be redirected to the site of the tumor?
- Cancer and inflammation: promise for biologic therapy.
- The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC.
- Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection.
- Editorial Board 2010 American Journal of Translational Research (ISSN 1943-8141): www.ajtr.org Publisher: e-Century Publishing Corporation (www.e-Century.org).
- PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer.
- Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
- Intracellular signaling molecules.
- Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma.
- Regression of recurrent Respiratory papillomatosis with celecoxib and erlotinib combination therapy.
- Chronic inflammation, Chronic obstructive pulmonary disease, and lung cancer.
- IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer.
- Lung cancer and Chronic obstructive pulmonary disease: needs and opportunities for integrated research.
- Editorial Board 2009: American Journal of Translational Research (ISSN 1943-8141) www.ajtr.orgPublisher: e-Century Publishing Corporation (www.e-Century.org).
- The launch of the american journal of translational research.
- Smoking and lung cancer: the role of inflammation.
- The partners--airflow obstruction, emphysema, and lung cancer.
- Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase.
- Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer.
- Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline ...
- Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance.
- The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer.
- EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells.
- Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase.
- Green tea induces annexin-I expression in human lung adenocarcinoma A549 cells: involvement of annexin-I in actin remodeling.
- Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system.
- A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer.
- IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer.
- Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.
- IntraPulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
- CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis.
- Celecoxib decreases Ki-67 proliferative index in active smokers.
- Aromatase inhibitors in human lung cancer therapy.
- Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
- PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells.
- Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.
- IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
- Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses.
- Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth fac...
- Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer.
- Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer.
- Dominant B cell epitope from NY-ESO-1 recognized by sera from a wide spectrum of cancer patients: implications as a potential biomarker.
- CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
- Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix.
- Modulation of Pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide.
- Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer.
- Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture?
- Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmona...
- Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity.
- COX-2 inhibition and lung cancer.
- Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.
- EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model.
- Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers.
- Methanandamide increases COX-2 expression and tumor growth in murine lung cancer.
- Interleukin-7 gene-modified dendritic cells reduce Pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
- Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells.
- IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity.
- Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
- Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells.
- Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism.
- Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models.
- Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer.
- Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
- Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu.
- Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4.
- IL-7 inhibits fibroblast TGF-beta production and signaling in Pulmonary fibrosis.
- Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta.
Schools
University of Medicine And Dentistry of New Jersey Newark
University Hospital
UCLA
Massachusetts General Hospital
Procedures Preformed
- Bronchoscopy
- Ventilation Management
Conditions Treated
- Alkalosis
- Chronic Pulmonary Heart Diseases (incl. Pulmonary Hypertension)
- Pneumonia
- Pulmonary Hypertension
- View All
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Awards
- Super Doctor
Education
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Massachusetts General Hospital -
Harvard Medical School -
UMDNJ-University Hospital -
Rutgers New Jersey Medical School
Hospital
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Cedars-Sinai Medical Center -
LAC-Olive View-UCLA Medical Center -
Ronald Reagan UCLA Medical Center
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