Professor of Medicine, Keck School of Medicine USC
Gastroenterology
Dr. Shelly C. Lu, MD
|
|
Give Review
Shelly practices Gastroenterology. She went to David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is a top medical college. David Geffen School of Medicine at UCLA is ranked 13/7 in Research/PrimaryCare. She over the years received 3 awards: "Mayo Soley Award for Lifetime Achievement in Science and Mentoring", "Outstanding Women in Science" and "Elected Member". Shelly is a published doctor as well. She has 100 publications published. The latest was: Disparity in liver cancer incidence and chronic liver disease mortality by nativity in Hispanics: The Multiethnic Cohort. She is registered with Medicare and accepts Medicare payments.
Publications
- Occidiofungin is an important component responsible for the antifungal activity of Burkholderia pyrrocinia strain Lyc2.
- Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.
- Sex and Ethnic Differences in the Association of Obesity With Risk of Hepatocellular Carcinoma.
- Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes.
- Disparity in liver Cancer incidence and chronic liver disease mortality by nativity in Hispanics: The Multiethnic Cohort.
- Methionine Adenosyltransferase 2B-GIT1 Complex Serves as a Scaffold to Regulate Ras/Raf/MEK1/2 Activity in Human Liver and Colon Cancer Cells.
- Magnetic bead and gold nanoparticle probes based immunoassay for β-casein detection in bovine milk samples.
- Real-time immuno-PCR for ultrasensitive detection of pyrene and other homologous PAHs.
- Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver Cancer.
- S-Adenosylmethionine and methylthioadenosine inhibit β-catenin signaling by multiple mechanisms in liver and colon Cancer.
- Diabetes and racial/ethnic differences in hepatocellular carcinoma risk: the Multiethnic Cohort.
- TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency.
- Gold nanoparticle aggregation-based colorimetric assay for β-casein detection in bovine milk samples.
- Enzyme-antibody dual labeled gold nanoparticles probe for ultrasensitive detection of κ-casein in bovine milk samples.
- Association of Coffee Intake with Reduced Incidence of Liver Cancer and Death from Chronic Liver Disease in the US Multiethnic Cohort.
- Activation of a Novel c-Myc-miR27-Prohibitin 1 Circuitry in Cholestatic Liver Injury Inhibits GSH Synthesis in Mice.
- Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance.
- S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome.
- Molecular Mechanisms of Lipopolysaccharide-mediated Inhibition of Glutathione Synthesis in Mice.
- Methionine Adenosyltransferase 2B, HuR, and Sirtuin 1 Protein Cross-talk Impacts on the Effect of Resveratrol on Apoptosis and Growth in Liver Cancer Cells.
- Glutathione synthesis.
- Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver Cancer.
- Methionine adenosyltransferase 2B-GIT1 interplay activates MEK1-ERK1/2 to induce growth in human liver and colon Cancer.
- MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma.
- Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine.
- Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon Cancer in mice.
- Where are we in the search for noninvasive nonalcoholic steatoHepatitis biomarkers?
- Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in mice.
- Inhibition of human methionine adenosyltransferase 1A transcription by coding region methylation.
- High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver Disease progression in mice.
- Role of AMP-activated protein kinase in the control of hepatocyte priming and proliferation during liver regeneration.
- Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon Cancer cells.
- The hepatocarcinogenic effect of methionine and choline deficient diets: an adaptation to the Warburg effect?
- Sub-proteome approach to the knowledge of liver.
- Non-alcoholic fatty liver Disease proteomics.
- S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes.
- Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice.
- Activation of LKB1-Akt pathway independent of phosphoinositide 3-kinase plays a critical role in the proliferation of hepatocellular carcinoma from nonalcoholic steato...
- Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression o...
- Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide.
- Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion.
- Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
- Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants.
- Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice.
- Where are we in the chemoprevention of hepatocellular carcinoma?
- S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes.
- Overview of extracellular microvesicles in drug metabolism.
- Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic live...
- HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
- Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation.
- Nonalcoholic steatoHepatitis, animal models, and biomarkers: what is new?
- Impaired liver regeneration in mice lacking glycine N-methyltransferase.
- Identification and characterization of an Nrf2-mediated ARE upstream of the rat glutamate cysteine ligase catalytic subunit gene (GCLC).
- S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model.
- Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications.
- S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon Cancer cells.
- Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes.
- Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide...
- CD133+ liver Cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis.
- Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes.
- Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms.
- Non-alcoholic steatohepatitis and animal models: understanding the human Disease.
- S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 stability: implication in hepatocarcinogenesis.
- Requirement of RIZ1 for Cancer prevention by methyl-balanced diet.
- S-adenosylmethionine and proliferation: new pathways, new targets.
- Antioxidants in the treatment of chronic liver Diseases: why is the efficacy evidence so weak in humans?
- Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice.
- Emerging role of epigenetics in the actions of alcohol.
- Regulation of glutathione synthesis.
- S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation.
- Alcohol, cofactors and the genetics of hepatocellular carcinoma.
- S-Adenosylmethionine in cell growth, apoptosis and liver Cancer.
- Methionine metabolism and liver Disease.
- Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
- Epigallocatechin-3-gallate inhibits growth of activated hepatic stellate cells by enhancing the capacity of glutathione synthesis.
- Expansion of liver Cancer stem cells during aging in methionine adenosyltransferase 1A-deficient mice.
- Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells.
- Leptin's mitogenic effect in human liver Cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta.
- Effects of hepatocyte growth factor on glutathione synthesis, growth, and apoptosis is cell density-dependent.
- Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma.
- Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon Cancer cells.
- Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver Disease: summary of a symposium.
- Role of S-adenosyl-L-methionine in liver health and injury.
- Identification of a gene-pathway associated with non-alcoholic steatoHepatitis.
- Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells.
- Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver Disease.
- Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.
- S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase.
- S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.
- Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver Diseases.
- Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis.
- Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver Cancer.
- Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1.
- Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1.
- Cloning and characterization of the human glutathione synthetase 5''-flanking region.
- Homocysteine, the bad thiol.
- Keratin mutation primes mouse liver to oxidative injury.
- 15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis.
- Methylthioadenosine.
Schools
University of California At Los Angeles
Cedars Sinai Med Center
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
Conditions Treated
- Abdominal Pain
- Anemia
- Benign Neoplasm of the Digestive System
- Cholecystitis and Gallstones
- View All
Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- Mayo Soley Award for Lifetime Achievement in Science and Mentoring
- Outstanding Women in Science
- Elected Member
Education
-
Cedars-Sinai Medical Center -
David Geffen School of Medicine at UCLA
Hospital
-
Cedars-Sinai Medical Center
Drug Facts
| NPI NUMBER | 1386673606 | |
| NPPES Provider LastName | LU | |
| NPPES Provider FirstName | SHELLY | |
| NPPES Provider ZIPCode | 900335310 | |
| NPPES Provider State | CA | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 57.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1386673606 |
| Last Name Of The Provider | LU |
| First Name Of The Provider | SHELLY |
| View All |
Similar Doctors
|
|
Dr. Yasser M. Bhat, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Barry A. Morguelan, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Wendy W. Ho, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Pilsoo Oh, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Timothy C. Simmons, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Laurie D. Deleve, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Tram T. Tran, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Paul H. Guth, MD
This Doctor is OpenDoctor Recommended.
 This doctor has more publications
|
|
|
Dr. Daniel W. Hommes, MD
This Doctor is OpenDoctor Recommended.
This doctor has more publications
|